It's all highly speculative, of course, but apparently Danny Boyle made mention of the possibility at a South by Southwest screening for footage of his upcoming effort, Trance.
"This has been a long time coming," Boyle told the Playlist after revealing footage from his upcoming film, Trance. "There's always been this long-term plan for Trainspotting 2. If [original screenwriter John Hodge] can produce a decent enough script, I don't think there will be any barriers to Ewan or any of the cast coming back."
Well, for starters, let's hope they don't call it Trainspotting 2. For continuers, it seems a dubious prospect to furnish a sequel to this film, and I say that as a total fan of the first one. For continuers of the continuers, have you ever read the book, as it was first released? I tried to read a paperback copy I bought in London and could not make a damn lick of sense out of it. I remember when I saw it at the Egyptian with my older brother (thinking I was so cool for being a nine-year-old and seeing an R-rated movie), when they passed out a key to Scottish slang before the curtains. Trance trailer, starring that rich kid from Shameless, after the cut.