Wonkette says it all, in a post titled "Yes, Please." Here's a quote from the conservative Boston Herald:
Massachusetts Republicans are desperately scrambling to find a strong Senate candidate to replace Scott Brown, with some even trying to persuade Mitt Romney’s wife or son to jump into the race to avert another electoral disaster. [...]
“I’ve had several people call me and ask about Ann Romney,” Ron Kaufman, a longtime friend and aide to the former Massachusetts governor and 2012 presidential candidate nominee, told the Herald.
This would make me so happy. I would travel to Boston with my own money and follow Ann Romney's senatorial campaign around. It would be the most entertaining three months of my life. Unfortunately, it's just not going to happen, because Ann Romney doesn't give a shit. Tagg Romney is a much more likely prospect, but I have a feeling he wants to wait for some of the loser stench to wash off the Romney name before he runs for office. I think we're still maybe four years away from Peak Tagg.