I am generally fond of the Philip K. Dick Awards, which are handed out annually at Norwescon. I wrote an article about why I love them so much last year:

The best reason to pay attention to Norwescon is the Philip K. Dick Awards, an annual ceremony dedicated to celebrating a "distinguished original science-fiction paperback published for the first time during the award year in the USA." Unlike most book awards, the PKD Awards almost always single out an excellent book. Of the last five years' worth of PKD winners, three of them—Life by Gwyneth Jones, Altered Carbon by Richard Morgan, and The Mount by Carol Emshwiller—are books that, in a world unprejudiced to genre, would wind up on almost any critics' annual best-of lists.

This year's Dick Award was a tie between two books, Adam-Troy Castro's Emissaries From the Dead and Terminal Mind by David Walton.

Here is the beginning of Sci Fi Weekly's review of Castro's Emissaries:

The Diplomatic Corps sends Counselor Andrea Cort to investigate a murder of one of the humans studying a massive deep-space artificial ecosystem called One One One, created by ancient artificial intelligences called the AIsource.

Years in the future, the U.S. is a splintered country. The city-state of Philadelphia is ripe for revolution. Mark McGovern, the son of a rich politician, lives in a world of expensive parties and frivolous biological mods, a sharp contrast to the poor underworld of his best friend, Darin Kinsley. When the two accidentally release a sophisticated virus called a 'slicer' into the net, Mark must try to stem the tide of casualties before the charged political situation explodes. But the slicer is more than a virus. To destroy it, Mark must first sort truth from lies, not only for himself, but for the mind of the child who holds his fate.

I have not read either one, but if you're into sci-fi and you're shopping for books, you should take a look at either of these books.