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don't you WANT some of your opiod receptors left after that?

Posted by max solomon | May 23, 2008 2:24 PM

This will only work for opioid addiction, her crack-smoking can continue unabated.

Posted by NaFun | May 23, 2008 2:30 PM

Remember that experiment where they wired up the monkey with direct electrical stimulation of the pleasure center? There was a button in the cage he could push which would give a little jolt of pure pleasure. So of course, he'd press that button as often as he could. Then they made it so that he had to press it more than once to get a jolt, and he did. So, they kept increasing the number of button pushes required to see when he'd say "Oh, fuck it--I guess it just doesn't work any more!!!"

After the count reached 20K, the researchers gave up. Poor chimpy would stay there hitting that button as fast as he could, forgoing water, food, sleep and sex.

That's what a real drug addict is like. You could burn out all the opiate receptors from AW's brain, and fuck me if she wouldn't spend the rest of her (short) life trying to find some combination of paint-thinner, banana skins and lye that wouldn't get her off.

Posted by Tiktok | May 23, 2008 3:09 PM

bravo @ #1 - what if some day you need those endorphin receptors, like during surgery or post-op?

Posted by E | May 23, 2008 3:55 PM

So, the way to get people off drugs -

- is to give them other drugs?

Posted by COMTE | May 23, 2008 4:00 PM

Actually, I blv the lyric is "70 days," even though she smack-shootingly pronounces it in an odd way.
Elsewhere in the song she says she "ain't gonna spend 10 weeks/have everyone think I'm on the mend."

Posted by doherty | May 23, 2008 4:23 PM

ANR can't possibly be any stupider than 28 days of institutionalized 12-Stepping.

Posted by Hooty Sapperticker | May 23, 2008 4:31 PM

$12,800, if the patient is considering that the price of recovery, is probably below what a real (er... I guess I mean "traditional") treatment program would cost.

Pretty damn skeptical of this though, even if his claims are real, conquering the chemical aspects of dependency is barely half the battle. Good old-fashioned 1950's Schick-Shadel aversion therapy is probably even more effective than this.

Destroying the pleasure receptors of a junkie sounds like a great way to set that junkie up to O.D. their first day out.

Posted by Dougsf | May 23, 2008 4:38 PM


Naltrexone isn't a 100% efficacious antagonist, so there's still going to be some endogenous opioid signaling going on during treatment. The idea is that you reset the opioid signaling machinery back to its pre-addiction state of equilibrium, not that you wipe it out entirely.

Posted by Bison | May 23, 2008 4:47 PM

What the hell is a drug-free Winehouse good for? I want to see her get a smoking-dolphin tattoo on her face and fall down vomiting on the Grammys next year.

Posted by Fnarf | May 23, 2008 5:09 PM

Poor Amy, she will never be able to sing again without wanting drugs.

Posted by crazycatguy | May 23, 2008 5:13 PM

Listening to her sing makes me want drugs, powerful painkillers.

Posted by Fnarf | May 23, 2008 5:45 PM

wait a second, i thought they already tried to send her there but she said, "No, No, No..."

Posted by longball | May 23, 2008 7:30 PM

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