Science Nice Figure
posted by July 25 at 13:19 PMon
Adult rat heart stained for cadherin, DNA, and filament actin (from the ever talented Veronica Muskheli).
The red staining is with phalloidin bound to rhodamine, a stain made from a mushroom poison that binds polymerized actin. When the heart cells beat, these bands of actin are pulled towards one another, causing the entire cell to forcefully shrink in length. The green staining is for cadherin—the protein that glues one cell to the next. Finally, the DNA is stained with a blue dye. This is a tough machine, capable of beating for a lifetime.